Independent. Not affiliated with Eli Lilly or Novo Nordisk.Not medical advice. Your prescriber decides your treatment.
GLP-1 Field GuidePractical help, sourced from the label

Sesame weight loss review

Sesame offers online weight-loss care with brand-name GLP-1s, with or without insurance, from one of the lowest membership prices we have seen. Here is what it costs and what to check first.

Compiled by the GLP-1 Field Guide editorUpdated 4 min readSourced from official labels. Not yet clinically reviewed.
Key points
  • Membership: from $59 a month on a 12-month commitment, covering video visits, labs and messaging.
  • Medicine is extra: self-pay from $149 a month (Wegovy pill), or as little as $25 with insurance.
  • Medicines: FDA-approved options including the Wegovy pill and pen, Zepbound and Foundayo.
  • Worth checking: the lowest price needs a 12-month commitment.

Sesame is a partner: we may earn a commission if you sign up through our links. Disclosure

Our take

Sesame is a good fit if you want brand-name medicine with ongoing video care at a low membership price, and you are happy to commit for a year to get it. It works with or without insurance. As with every program like this, the medicine is a separate cost, so add the two together when you compare.[1]

What it costs

Sesame lists ongoing video visits, dedicated provider care, labs and messaging from $59 a month, based on a 12-month commitment. Medicine is not included and depends on your insurance and pharmacy.[1] At the makers' self-pay prices, the Wegovy pill starts at $149 a month and Zepbound vials or KwikPen at $299 for the starting dose.[4, 5]

With the Wegovy pill$208 a month
$59$149
With Zepbound (2.5 mg)$358 a month
$59$299
Sesame membership (12-month plan)Medicine, self-pay starting dose
What a month could cost with Sesame if you pay for the medicine yourself. Prices from Sesame, Novo Nordisk and Lilly; medicine prices are checked weekly.

Medicines offered

Sesame's weight-loss page lists FDA-approved options including the Wegovy pill and pen, Zepbound (KwikPen and vials), Foundayo and Ozempic, with insurance or at a cash price. A clinician decides which, if any, is right for you.[1]

Good to know before you sign up

  • The $59 price needs a 12-month commitment. Shorter terms cost more.[1]
  • Medicine is billed separately. Your insurance, or a self-pay price, covers it.[1]
  • Read the cancellation and refund terms at checkout before you commit.

What customers say

Sesame has over 4,500 reviews on Trustpilot across all its services, with an overall score of 4.6 out of 5. Reviewers often praise kind, attentive clinicians and easy booking. The complaints mention providers not showing up for appointments, billing problems and slow support.[2]

Our checks

Every partner we link to is re-checked every month against five tests: LegitScript certification, FDA warning letters, lawsuits, how the medicine is supplied, and marketing claims.[3] Sesame passed all five on October 20, 2026. See how we check partners. Passing our checks is not a medical endorsement: whether a medicine is right for you is a clinician's decision.

Visit SesamePartner link. US residents only.

Comparing options? See online GLP-1 providers compared.

Common questions

Is Sesame legit for GLP-1 weight loss?

Sesame is a US online care marketplace where licensed clinicians can prescribe FDA-approved weight-loss medicines when appropriate. We confirmed its LegitScript certification on LegitScript's own website, and it passed our five partner checks on October 20, 2026.

How much does Sesame weight loss cost?

Sesame lists its weight-loss care, with video visits, labs and messaging, from $59 a month on a 12-month commitment. Medicine is not included: self-pay prices start at $149 a month for the Wegovy pill, and with insurance you may pay as little as $25.

Does Sesame take insurance for weight-loss medicine?

Sesame says insurance is accepted for weight-loss medications, and that medicine costs vary with your insurance and pharmacy. The membership itself is a separate monthly fee.

Not medical adviceThis guide explains what the official instructions say. Your prescriber and pharmacist know your situation, so ask them if anything here does not match what you were told.

Sources

  1. Sesame. Online weight loss medication with or without insurance. Revised n/a (web page). Last checked 2026-10-28.
  2. Trustpilot. Sesame reviews. Revised n/a (web page). Last checked 2026-10-28.
  3. LegitScript. Healthcare certification. Revised n/a (web page). Last checked 2026-10-06.
  4. Novo Nordisk. Wegovy savings, self pay and home delivery (NovoCare Pharmacy). Revised n/a (web page). Last checked 2026-11-04.
  5. Eli Lilly and Company. Zepbound savings and coverage options. Revised n/a (web page, programs through 12/31/2026). Last checked 2026-11-04.
Online GLP-1 providers comparedSesame side by side with the alternatives.Does insurance cover it?How to check, get approved and appeal.GLP-1 price checkerEvery brand and dose, checked weekly.How we check partnersThe five tests, re-run every month.